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The self-administration of medication programme can effectively increase patients' medication adherence and nurses' satisfaction. Despite Tricholoma matsutake has been used as natural health products with multiple medicinal properties, detailed information about its polyphenolic composition as sources of anti-photoaging agents remains to be determined. To investigate the impact of polyphenols extracted from Tricholoma matsutake (TME) on Ultraviolet B (UV-induced skin photoaging. Various factors of oxidative stress and inflammation as