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evaluating methods to optimize its real-world implementation. The current manuscript describes the rationale and design of a hybrid type 2 trial of self-sample HPV testing in a safety net health system. Trial findings are expected to provide meaningful data to inform screening strategies to ultimately realize the global goal of eliminating cervical cancer. ClinicalTrials.gov NCT03898167 . Registered on 01 April 2019. Study start data February 13, 2020. Recruitment status Enrolling by invitation. Estimated primary completion date February 1
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