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In this review, we summarize the roles of DNA damage proteins in unperturbed mitosis, analyze the molecular mechanisms involved, and discuss the potential implications of these findings in cancer therapy. © 2020 Federation of European Biochemical Societies.Although pure hydrogen cyanide can spontaneously polymerize or even explode, which is initiated by small amounts of bases (e.g. CN - ), the reaction of liquid HCN with [WCC]CN (WCC = weakly coordinating cation = Ph 4 P, Ph 3 PNPPh 3 = PNP) was investi-gated. Depending on the cation,