https://www.selleckchem.com/pr....oducts/pim447-lgh447
Brucella spp., are facultative intracellular bacteria notorious for their ability to induce a chronic, and often life-long, infection known as brucellosis. To date, no licensed vaccine exists for prevention of human disease, and mechanisms underlying chronic illness and immune evasion remain elusive. We and others have observed B cell deficient mice challenged with Brucella display reduced bacterial burden following infection, but the underlying mechanism has not been clearly defined. Here we show that at one-month post-infection,
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