https://www.selleckchem.com/pr....oducts/17-AAG(Geldan
Fanconi anemia (FA) is a rare chromosomal instability syndrome with various clinical features and high cancer incidence. Despite being a DNA repair disorder syndrome and a frequently observed clinical hypersensitivity of FA patients towards ionizing radiation, the experimental evidence regarding the efficiency of radiation-induced DNA double-strand break (DS repair in FA is very controversial. Here, we performed a thorough analysis of the repair of radiation-induced DSBs in G1 and G2 in FA fibroblasts of complementation g

https://www.selleckchem.com/pr....oducts/AZD2281(Olapa
The size of the retinal structures significantly increased with AL ( 0.001) and was well predicted by geometric scaling. Method 1 systematically underestimated the RGC counts by as much as 60%. No bias was observed with Method 2. The Drasdo model can effectively account for AL assuming geometric scaling. Method 2 should be used for structure-function analyses. We developed a free web App in Shiny R to make our results available for researchers. We developed a free web App in Shiny R to make our results available for resea