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How to Treat ADHD Without Medication Adults suffering from ADHD can struggle to remain focused, feel irritable and in a state of forgetfulness. They can also suffer from low self-esteem, relationship difficulties and chronic stress. Treatment without medication could include lifestyle changes such as eating healthy exercising regularly, and learning relaxation techniques. It might also involve cognitive behavioral therapy, which teaches people how to recognize and confront negative thoughts and behaviors. 1. Talk