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S. pneumoniae isolates from bloodstream, cerebrospinal liquid, pleural liquid and breathing secretions (sputum, bronchoalveolar lavage and nasopharyngeal swab/throat swab) had been analysed to determine ST, serotype and antimicrobial susceptibility pattern. Serotyping was done by multiplex polymerase string reactions in addition to by quellung response. Antimicrobial susceptibility testing had been determined making use of Kirby Bauer's disc diffusion technique as per the medical Laborat