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05). In the total sample, there was a gradual increase of OPN levels across subgroups with triphasic, biphasic, and monophasic/blunted waveforms (P less then .001). In conclusion, plasma OPN levels are associated with the presence and severity of LEAD in subjects with T2DM. Further studies are needed to investigate the role of OPN in the pathogenesis and progression of LEAD.Struma Ovarii is one of the types of mature teratoma, with predominant thyroid tissue (50%). It occurs in 1% of all cases of ovarian tumors and in 2.7% of dermo