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Non Stimulant ADHD Medication Stimulants increase dopamine and norepinephrine levels, neurotransmitters that help in enhancing alertness, thinking and effort, as well as motivation. They can also enhance focus and concentration. Non-stimulant ADHD medications are typically prescribed when stimulants fail to work and cause unacceptably adverse side effects or a person is unable to take them due to medical reasons. Examples of these include Clonidine (Kapvay) and guanfacine (