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87 to 0.96 for MSTs and from 0.58 to 0.87 for LSIs. The 95% confidence interval (CI) for a true value varied from ± 0.02 seconds (s) to ± 0.05 s for MSTs and from ± 4.6 percentage points (pp) to ± 6.6 pp for LSIs.Conclusion Mean step times measured with a body-fixed IMU during stair descent and limb symmetry indexes calculated from these mean step times are precise and reliable during early post-operative rehabilitation after ACLR and in healthy subjects.Purpose Osteoarthritis (OA) of the knee is a debilitating, expensive, and prevalent d