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Furthermore, when these changes are limited to the 2nd and 3rd fingernails, they should prompt the diagnosis of CTS. Once suspected, diagnostic evaluation is not difficult and surgical management can resolve cutaneous findings and prevent irreversible changes such as acroosteolysis. BACKGROUND A spectrum of skin disease severity exists in patients with recessive dystrophic epidermolysis bullosa (RDE. OBJECTIVE To characterize the patient reported outcomes and quality of life (QOL) in RDEB patients. METHODS A cross-sectional study of RD
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