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001). EQ-5D VAS was significantly lower (P = .011) in CRSsNP (mean 68.9) compared to CRSwNP (mean 73.2). However, CRSwNP patients reported significantly less symptom control, compared to CRSsNP, in association with nasal and emotional symptoms. Conclusion CRSwNP and CRSsNP have differences in symptom profile, effect on health-related QOL, and patient-perceived symptom control. CRSsNP experience significantly greater burden of ear/facial discomfort, while CRSwNP report greater hyposmia. Although CRSsNP reports lower general health-relat

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Methyl siloxanes are becoming increasingly prevalent in the environment because of their extensive use in various consumer products. Little is known about the distribution of these chemicals around factories or their presence in road dust. We conducted a survey of four cyclic (D3-D6) and 13 linear (L4-L16) siloxanes in road dusts around a manufacturing site and found a total siloxane concentration range of 47.3-3.16 × 103 ng/g (median 372). The predominant siloxanes in the road dust samples were D3, D4, D5, and D6, with median contribu