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While it is not likely to provide monotherapy for migraine headaches, it is a novel therapy that may be added for instances of extreme or frequent migraines.The opioid receptor (OPR) household includes the mu-, delta-, and kappa-opioid, and nociceptin receptors that belong into the superfamily of 7-transmembrane spanning G protein-coupled receptors (GPCRs). The mu-opioid receptor is the main target for clinically utilized opioid analgesics, and its biology has-been extensively studied. Th
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