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Endoglin expression in metastatic cases (0.68 + 0.1 was higher than nonmetastatic cases (0.45 + 0.2 and the difference was statistically significant ( = 0.002). This study shows that presence of endoglin determines the metastatic potential of the tumor and its prognosis, thus, could be considered as a potential target of therapy. This study shows that presence of endoglin determines the metastatic potential of the tumor and its prognosis, thus, could be considered as a potential target of therapy. Sepsis is a major worldwide cause of