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8%) developed local recurrence and one developed distant metastasis. Of the 17 patients, three were unwilling to undergo completion surgery. The median LRFI was 20 (range 7-6 months. Multivariate cox regression analyses showed that mitotic rate 10/high power field [hazard ratio (HR) 0.147; p=0.04], stromal overgrowth (HR 4.904; p=0.05), margin status (HR 0.037; p0.001), and preoperative neutrophil-to-lymphocyte ratio [(NLR), HR 4.891; p=0.04)] were significant predictors of LRFI. A high mitotic rate, positive margin, stro