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. This study is the first step towards investigating how parasite population structure might inform strategies to manage resurgence and elimination of lymphatic filariasis.Translation in eukaryotes is dependent on the activity of translation initiation factor (eIF) 4G family of proteins, a scaffold protein that, during the initiation step, coordinates the activity of other eIFs to recruit the 40S ribosomal subunit to the mRNA. Three decades of research on protein synthesis and its regulation has provided a wealth of evidence supporting th

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牽頭式債務舒緩計劃又稱綜合債務舒緩計劃，其實與債務舒緩計劃相似，同樣無需經過法庭程序，無需律師或會計師參與，可節省堂費、律師費等高額開支，亦能保持高私隱度。他們最大的相異之處，就是債務人只需向最大債權人（即牽頭銀行）協商，討論新的還款方案。因為無需與所有債權人逐個安排談判，申請手續得以簡化。 市面上有不少提供債務重組服務的機構，例如香港債務重組協會、盈富專業方案事務所等等，服務範圍覆蓋卡數、銀行個人貸款、金融公司貸款、高利息貸款、信用社貸款、學生助學貸款、稅收等等。 申請人與牽頭債權人經過洽談，若雙方接受新的還款建議，又獲得其餘債權人的同意，債務人所有債款便將歸納於牽頭債權人下，根據新方案規定的較低的利息，日後債務人只需每月向這個單一債權人定額定息還款，