https://www.selleckchem.com/pr....oducts/protac-tubuli
r, specific antimicrobial agents and vaccines development is ongoing. Aromatase, a cytochrome P450 hemoprotein that is responsible for estrogen biosynthesis by conversion of androgens into estrogens, has been an attractive target in the treatment of hormone- dependent breast cancer. Design of new steroidal aromatase inhibitors becomes imperative. Synthesis and biological evaluation of two classes of structurally and functionally diverse D-ring pregnenolone pyrazoles as type I aromatase inhibitors and antiproliferative
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