https://www.selleckchem.com/pr....oducts/acalabrutinib
EZH2 activated the nuclear factor-kappa B (NF-κ and p38 signaling pathways in HDPCs, the inhibition of which reversed the induction of MMPs and the suppression of type I collagen. EZH2 can downregulate the type I collagen levels in an experimental model of dental pulpitis in rats. EZH2 promotes extracellular matrix degradation via nuclear factor-κB (NF-κ and P38 signaling pathways in pulpitis. EZH2 can decrease the type I collagen levels in vivo and in vitro. Intravascular fluids are a necessary and universal component of card