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Methods FME was performed in 15 Barrett's neoplasia patients. EMI-137 had been administered to 3 cohorts of five patients 0.13 mg/kg intravenously (IV); 0.09 mg/kg IV or externally at a dose of 200 μg/cm BE (n=1) or 100 μg/cm feel (n=4). Fluorescence ended up being visualized in vivo, quantified in vivo using multi-diameter single-fiber reflectance, single-fiber fluorescence (MDSFR/SFF) spectroscopy and correlated to histopathology and immunohistochemistry