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It has been more than a decade since the first observational study on the clinical use of cytomegalovirus (CMV) cell-mediated immunity (CMI) was published in AJT. Since then, the promise of CMI has been consistent - high CMI results predict protection against CMV outcomes and low CMI increases the likelihood of CMV outcomes. This article is protected by copyright. All rights reserved.We read with pleasure the letter from Gruttadauria et al. (1) depicting an interesting case of poor hepatic artery (HA) flow due to portal hyperperfusion (P