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Peptidoglycan (PG) is an essential component of the bacterial cell wall and is assembled from a lipid II precursor by glycosyltransferase and transpeptidase reactions catalyzed in particular by bifunctional class A penicillin-binding proteins (aPBPs). In the major clinical pathogen Pseudomonas aeruginosa, PBP1B is anchored within the cytoplasmic membrane but regulated by a bespoke outer membrane-localized lipoprotein known as LpoP. Here, we report the structure of LpoP, showing an extended N-terminal, flexible tether followed by a well

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Best Twin Stroller For Newborns A double stroller is essential if you are expecting twins or have two children who are similar in age. The best double strollers offer numerous ways to ride your children with side-by-side seating and an attachment for boards. Strategist writer Lauren Ro's favorite is the Bugaboo Donkey 5 Mono, which is easily adapted as your family grows. It can be used with two infant car seats as well as a toddler seat. This makes it an excellent choice fo