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This effect was significantly stronger in women than in men (p-interaction = 0.01. Survival decreased with higher CCI, tumor stage and age in all CRC patients. Sex had no impact on survival. The probability of receiving any primary treatment and survival were independent of sex. However, female CRC patients with the highest CCI appeared more likely to receive other therapy than surgery compared to their male counterparts. The probability of receiving any primary treatment and survival were independent of sex. However, female CRC patien