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Structure-biological scientific studies recommend two methods of activation in the band carbon atoms and also at the pyrrole nitrogen. Its supposed that the specific pathway of biotransformation might be associated with the tissue/organ specificity of DBC. Cytochrome P450 (CYP) family members of enzymes plays a pivotal role into the metabolic process of DBC; though, the one-electron activation and the aldo-keto reductase-catalyzed oxidation will also be tangled up in metabolic activati