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12 [95% CI 1.04-1.21]). This study targeted people aged 40years, thereby narrowing the search to the risk factors of late-onset psoriasis. We showed that increasing age, male sex, body mass index, smoking, low physical activity, weight gain, and gamma-glutamyl transpeptidase are associated with late-onset development of psoriasis and revealed a relationship between liver dysfunction and psoriasis development. We showed that increasing age, male sex, body mass index, smoking, low physical activity, weight gain