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Robust in vitro and in vivo PK/pharmacodynamic (PD) data support the ability of this dosing regimen to achieve specified PK/PD targets for both bactericidal activity and prevention of resistance among pathogens with MICs up to 8 mg/l. This concerted effort into optimizing the PK and PD parameters of both the β-lactam and β-lactamase inhibitor alone and in combination contributed to the clinical success of meropenem-vaborbactam demonstrated in phase 3 trials in patients with complicated urinary tract infections (cUTI), including acute p

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Other teams now in Opisthokonta (e.g., Corallochytrium, Ichthyosporea) have been additionally at given time categorized as fungi. The genus Blastocystis, now in Stramenopiles, was originally categorized as a yeast. The bacteria have been also included in fungi in some classifications, because the group Schizomycetes. Compared to very large quantity of research carried out on infectious bacteria or viruses, most fungal infection research is conducted by small teams or people. There are solely a handful of bigger analysis centres all over t