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The 3D structural analysis and functional forecast revealed that all these eight alternatives may influence AMPAR appearance or function, and influence the synaptic plasticity by regulating the palmitoylation of PSD95 and AKAP79/150. CONCLUSION Our results first show powerful supporting evidences for the association amongst the ZDHHC2 and SCZ, as well as provide a fine-mapping of variants with this gene in Han Chinese SCZ c