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We describe an approach for targeted epigenomic liquid biopsy in pregnancy and discuss our results when you look at the context of noninvasive prenatal examination with regards to phenotypic maternity monitoring in addition to early recognition of complex gestational phenotypes such as preeclampsia and preterm birth.We describe a method for targeted epigenomic liquid biopsy in maternity and talk about our findings in the context of noninvasive prenatal screening with respe