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6% P less then 0.001). The proportion of patients with NEDA was 94% in the group of RMS patients who were followed for at least 1 year. Ocrelizumab was generally well-tolerated; the most common adverse events were infusion-related reactions and infections, none of which were serious. Conclusions Our real-world study supports the tolerability, safety, and effectiveness of ocrelizumab in clinical practice.BackgroundSCN1A and SCN2A genes have been reported to be associated with the efficacy of single and combined antiepileptic therapy, but