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Nevertheless, the pharmacological activities of flavor compounds in Maotai alcohol haven't been completely elucidated. In answering this concern, a system-level evaluation was developed by combining in silico ADME assessment, multi-target prediction, GO enrichment evaluation, system pharmacology technology, path analysis, as well as experimental verification to elucidate the pharmacological effects of flavor substances in Maotai alcohol. Eventually, 55 energetic substances and 80 targets were i