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To investigate SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 ( ) gene expression across The Cancer Genome Atlas (TCGA) cancers, both in cancer versus normal tissues and in different stages across the cancer types. This integrated bioinformatics study used data from several bioinformatics databases (Cancer Cell Line Encyclopedia, Genotype-Tissue Expression, TCGA, Tumor Immune Estimation Resource [TIMER]) to define the expression pattern of the gene. A survival analysis was undertaken across the cancers. The search tool