https://www.selleckchem.com/pr....oducts/z-lehd-fmk-s7
001). In both sides, significant differences in the timed 360° turn test times were found between PwPD and healthy people and between fallers and non-fallers with PD (p  less then  0.001 and p  less then  0.001, respectively). The timed 360° turn test times of 3.76-3.89 s were found to best discriminate PwPD from healthy people, while 5.46-5.74 s were found to best discriminate fallers from non-fallers with PD. The minimum detectable change in the timed 360° turn test times were 1.98 s for dominant side and 1.48 s for non-domin

https://www.selleckchem.com/pr....oducts/azd0156-azd-0
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have led to great advances in the treatment of non-small cell lung cancer (NSCLC), but the emergence of drug resistance severely limits their clinical use. Thus, elucidation of the mechanism underlying resistance to EGFR-TKIs is of great importance. In our study, sustained activation of STAT3 was confirmed to be involved in resistance to EGFR-TKIs, and this resistance occurred regardless of exposure time, EGFR-TKIs type, and even cancer cell type. Mechanist