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How Does ADHD Medication Work? When a neuron transmits an information to another, it uses chemicals called neurotransmitters. They must cross a tiny gap called a synapse. Some ADHD medications boost the effectiveness of these messages. They either help neurons release neurotransmitters more frequently or slow down the reuptake (called Reuptake inhibitors). Doctors start people with ADHD on a low dose of medication, and then monitor their responses. They alter the dosage over time to
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