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Finally, the candidate objectives were examined by molecular docking. The results proposed that HCQ when you look at the treatment of RA had been mainly connected with 4 objectives being smoothened homolog (SMO), sphingosine kinase (SPHK) 1, SPHK2 and gatty-acid amide hydrolase (FAAH), using their associated 3276 proteins' network which regulate ErbB, HIF-1, NF-κB, FoxO, chemokines, MAPK, PI3K/Akt paths and so on. Biological process were mainly focused within the legislation of mobile activ
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