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6%) and 35 (19.2%) developed new d2 and d3 lesions, respectively. Both varnishes reduced the incidence of caries compared with the control group, but there was no significant difference between group A and group B. Compared with group C, the relative risk for developing cavitated lesions was 0.39 (95% CI 0.22-0.62) in group A and 0.26 (95% CI 0.14-0.5 in group B. The total prevented fraction (Δd2d3mft) for group A and group B was 19.9 and 22.5% (p less then 0.05), respectively. No adverse effects were observed or reported during the s