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Placing a cover plate over the device formed microtraps, the size of which was defined by the width and depth of the cross-channels. This microfluidic chip allowed for automation of immunofluorescence and FISH, requiring the use of small volumes of reagents, such as antibodies and probes, as compared to slide-based immunophenotyping and FISH. In addition, the device could secure FISH results in less then 4 h compared to 2-3 days for conventional FISH.In 2017, the European Commission published Regulation 2017/2158 establishing mitigat

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