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RESULTS At a mean follow-up of 46±17 months, mean subjective IKDC was 67.8±23; KOOS scores were symptoms, 78±22; pain, 78±23; function, 85±20; sports, 66±27; and activities of daily living, 59±25. MRI MOCART score revealed incomplete scaffold healing in 21.4% of cases, with variable signal intensity within regenerated tissue. Functional scores did not correlate with reconstruction aspect on MRI. DISCUSSION/CONCLUSION 3D collagen scaffolds yield good medium-term clinical outcomes in large osteochondral defects of the knee. There is, howe