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The preparation protocols remain the key to these achievements. However, the chemical techniques are not friendly ecologically and may hydrolytically degrade the chitin. The biological processes using enzymes or microorganisms are much better but still inefficient. Besides, the processing time limits the rapid preparation of the fibrils in the long-term perspective.Structural proteins such as spider silk and silkworm silk are generally poorly soluble in aqueous and organic solutions, making them difficult to manipulate in manufacturing
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