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These results suggest that parasite populations with reduced artemisinin sensitivity are more transcriptionally heterogenous. This pattern is consistent with a model where the parasite utilizes bet-hedging strategies to diversify the population, rendering a subpopulation more able to navigate drug treatment. To evaluate the safety and effectiveness of a compliant multi-electrode radiofrequency balloon catheter (RF used with a multi-electrode diagnostic catheter for pulmonary vein isolation (PVI). This prospective, multic

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