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Biocompatibility assay ended up being carried out to look for the safe focus selection of polymer. The assay of fluorescent distribution in vivo shown that LKTM is effectively delivered to thrombi in vivo. Thrombolysis in vivo indicated the thrombolytic strength of LKTM ended up being ideal in every teams. Notably, the laboratory mice treated with LKTM exhibited a significantly smaller tail hemorrhaging time when compared with those addressed with LK or LK-loaded micelles without RGDfk,