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The distinction between livestock-associated and human-associated methicillin-resistant (MRSA) has become more and more blurred. This study aimed to reveal the transmission risk of livestock-associated and non-livestock-associated (including MRSA and multidrug-resistant [MDRSA]) by occupational pig exposure. A total of 591 pig-exposed workers and 1178 non-exposed workers were enrolled in this study. All nasal isolates were tested for antibiotic susceptibility and molecular characteristics. Logistic regression models were used to examine