https://www.selleckchem.com/products/odm-201.html
TLR3 signalling induced expression of proinflammatory cytokines at the gene level, indicating that several PRRs need to interact for successful innate immune activation. The inflammatory responsiveness of HLCs was accompanied by the downregulation of cytochrome P450 3A and 1A2 activity and decreased serum protein production, showing that the metabolic switch seen in primary hepatocytes during anti-viral responses is also present in HLCs.Piezo channels are mechanosensitive ion channels. Piezo1 is primarily expressed in nonsensory tissues
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