https://www.selleckchem.com/pr....oducts/azd0156-azd-0
7%) patients with UC compared with 2378/6960 (34.2%) patients with CD (p0.0001). This difference was corroborated in a multivariable analysis after adjusting for variables including treatment era, thiopurine monotherapy was less effective in CD than UC (OR 0.47, 95% CI 0.43 to 0.51, p0.0001). Thiopurine intolerance was associated with increased risk of surgery in UC (HR 2.44, p0.0001); with a more modest impact on need for surgery in CD (HR=1.23, p=0.0015). Thiopurine monotherapy is an effective long-term treatment
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