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The solubility of a compound is one of its most important properties. Here, regression relationships are presented for solubilities of a series of gases in water and in four organic solvents, treating each solvent separately. The solubilities are related to the Coulombic intermolecular interactions arising from the intrinsic polarities of the solute molecules and the polarities induced in them by the solvent. As a measure of intrinsic polarity, a statistical quantity defined in terms of the solute's molecular electrostatic potential is us