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Reducing the peak time of an epidemic disease in order for slowing down the eventual dynamics and getting prepared for the unavoidable epidemic wave is utmost significant to fight against the risks of a contagious epidemic disease. To serve to this purpose, the well-documented infection model of SIR is examined in the current research to propose an analytical approach for providing an explicit formula associated with a straightforward computation of peak time of outbreak. Initially, the time scale from the relevant autonomous SIR epi

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B cells express various ion channels, but the presence of voltage-gated sodium (NaV) channels has not been confirmed in the plasma membrane yet. In this study, we have identified several NaV channels, which are expressed in the human B cell membrane, by electrophysiological and molecular biology methods. The sensitivity of the detected sodium current to tetrodotoxin was between the values published for TTX-sensitive and TTX-insensitive channels, which suggests the co-existence of multiple NaV1 subtypes in the B cell membrane. This was