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44 (1.19-5.04), p=0.015). PADI4 rs2240340 was linked to CHAQ score (genotype p=0.013, allele p=0.006), whilst PDCD1 rs10204525 was linked to Anti-CCP antibodies (genotypes p=0.004), RF (genotypes p=0.01), and the CHAQ score (genotype p=0.005, allele p=0.013).Conclusions There are various roles for these SNPs in PADI4, CTLA4 and PDCD1 in the diagnosis and, potentially, in the management of JIA.Devoted actors-those who share sacred values with a group with which they are fused-are particularly willing to self-sacrifice to defend their gro