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Right here, we investigated the safety and molecular ramifications of two RAS modifiers, aliskiren; renin inhibitor and captopril; angiotensin transforming enzyme inhibitor, on intellectual deficits within the rat hippocampus. Shot of reduced dose streptozotocin for 4 days lead to type 1 diabetes. Then, badly controlled diabetes was mimicked with inadequate day-to-day doses of insulin for 4 months. The hyperglycaemia and pancreatic atrophy caused memory disturbance that were identifiable in behavioural t
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