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Biliary tract cancer, and intrahepatic cholangiocarcinoma (iCC) in particular, represents a rather uncommon, highly aggressive malignancy with unfavorable prognosis. Therapeutic options remain scarce, with platinum-based chemotherapy is being considered as the gold standard for the management of advanced disease. Comprehensive molecular profiling of tumor tissue biopsies, utilizing multi-omics approaches, enabled the identification of iCC's intratumor heterogeneity and paved the way for the introduction of novel targeted therapies und

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Benefits of a Treadmill With Desk Many people spend long periods of their working lives sitting down. This can cause range of health issues, including weight gain, back problems and a decrease in fitness levels. Treadmill desks allow you to increase daily activity and reduce the time spent at your desk. This reduces the risk of developing chronic illnesses and improve cardiovascular health. If used often, a treadmill with desk can help users improve their daily physical activity. This is cruci