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aPDT-0.5 also lead in higher immunolabeling patterns of TGF-ß1 at all periods (p less then 0.05) and of OCN at thirty days (p less then 0.05). Conclusion aPDT-0.5 showed the best advantages for inflammatory reaction and periodontal repair procedure.Objective the goal of the present study was to evaluate the effectation of various photosensitizers activated by photodynamic therapy (PDT) on shear bond strength (SBS) of composite resin on caries affected dentin when