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Functional gadolinium(3)-phthalocyaninate photoagent regarding MR/PA imaging-guided parallel photocavitation and also photodynamic oxidation at single-laser irradiation. Moreover, significant increase in the activities of testicular lactate dehydrogenase and γ-glutamyl transferase was observed, with significant decrease in the activities of acid phosphatase and alkaline phosphatase relative to finasteride-treated rats. Furthermore, hesperidin exhibited favorable binding affinity fo