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Alginate-g-polyethylene glycol methacrylate xerogels cross-linked with strontium ions (AGPMS) were developed for wound healing applications. Grafting improved the mechanical properties of alginate xerogel significantly. Strontium cross-linking further strengthened the xerogel. There was a 4.4 fold increase in tensile strength of AGPMS xerogel compared to that of strontium cross-linked alginate. The amount of Sr2+ was quantified to be 5.144 mg/g of the xerogel and its release in phosphate buffer (pH 7.4) was 55 ± 3.18% by 72 h. An ionic c

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